Scientists from the University of Portsmouth and the University of Manchester say they have developed a fusion enzyme that ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

Clascoterone (cortexolone 17α-propionate) is a first-in-class topical anti-androgen approved in 2020 for the treatment of acne in patients aged 12 years and older. It works by blocking androgen ...

One of the main challenges of second-generation biofuel production is identifying enzymes produced by microorganisms for use in a cocktail of enzymes to catalyze biomass hydrolysis in which the ...

How can we know what life on Earth looked like more than three billion years ago, when rocks from that era are so rare and difficult to exploit? To answer this question, researchers have adopted ...

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule. The anti-cancer molecule salinosporamide A, also called Marizomb, is in Phase III clinical ...

A new study finds enhanced activity of a specific enzyme drives spinocerebellar ataxia type 14, which suggests inhibiting the enzyme may have therapeutic potential. pinocerebellar ataxias are a group ...