Q&A: What do scientists need to learn next about blocking enzymes to treat disease?

Enzymes are the molecular machines that power life; they build and break down molecules, copy DNA, digest food, and drive ...

Scientists identify promising new target for Alzheimer's-linked brain inflammation

A multidisciplinary team has developed a selective compound that inhibits an enzyme tied to inflammation in people at genetic ...

A new strategy to beat lung cancer: Chemists develop first-in-class inhibitor targeting a key epigenetic regulator

A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...
News Medical

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

In a recent study published in the Journal of Computational Biology and Chemistry, researchers identified curcumin derivatives as potential inhibitors of severe acute respiratory syndrome ...
BioTechniques

Antiviral insights: cryo-EM and optical tweezers reveal more about drug–herpes virus interaction

Researchers use cryo-EM and optical tweezers to investigate how an antiviral interacts with the herpes simplex virus.
GEN

Metabolic Enzyme Inhibition Kills Melanoma Cells, Stops Tumor Growth

3D structure of a melanoma cell derived by ion abrasion scanning electron microscopy [National Cancer Institute (NCI). Image created by Sriram Subramaniam, NCI] Researchers at Sanford Burnham Prebys ...

Blocking key enzyme to protect against fatty liver may raise cancer risk instead

Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead ...