The inhibitor and substrate compete for the same binding site (or the active site) on the enzyme. The inhibitor decreases the enzyme’s capacity to bind the substrate, but this impact may be ...

In the world of biochemistry, knowing that a reaction is “fast” isn’t quite enough. To truly understand a biological catalyst, we need to know exactly how hard a single molecule of that enzyme is ...

Abstract: Optimization of the enzyme turnover rate kcat in enzyme-constrained metabolic models, such as S. cerevisiae’s ecYeastGEM, is essential to improve the accuracy of cellular metabolism ...

Researchers have discovered that the enzyme OTULIN, known for regulating the immune system, also drives the formation of tau – a protein linked to Alzheimer’s and other neurodegenerative diseases. In ...

Roasted coffee may do more than wake you up—it could help control blood sugar. Researchers discovered several new coffee compounds that inhibit α-glucosidase, a key enzyme linked to type 2 diabetes.