For some, January is a time for resolutions, with the goal often tied to being fitter and healthier. And increasingly this ...

Scientists have discovered how exercise protects aging muscles by suppressing DEAF1, a molecule they identified as a driver ...

Working out doesn't just build muscle but, in later life, helps maintain a powerful cellular machine that repairs damaged ...

An international team of scientists, led by Nanyang Technological University, Singapore (NTU Singapore), has discovered a new ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...

aThe Cardiac Exercise Research Group at the Faculty of Medicine and Health Sciences, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway ...

Potential first-in-class, and industry-leading DNA polymerase Theta (Polθ) inhibitor, ART6043 demonstrated an attractive tolerability profile, expected PK/PD activity, and promising clinical signals ...

Naked mole-rats are well known for both their wrinkly appearance and for their unexpectedly long lives. The source of this extended lifespan has been under scrutiny for decades. While many rodents are ...

Objectives: In patients surviving myocardial infarction (MI), adipose tissue infiltration within the scar is a common pathologic finding and may contribute to dysfunction and arrhythmogenesis. However ...

This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...

Figure 1. Stem cell populations involved in lung regeneration and repair after injury. After airway damage, basal cells have the capacity to differentiate into both club cells and ciliated cells. Club ...